Current trends in needle-free jet injection: an update
نویسندگان
چکیده
منابع مشابه
Needle-Free Jet Injection Revisited
Jet injection was developed in the 1940’s, conceived by Robert Hingson and invented by Oscar Banker, to vaccinate billions of people who needed immunizations with the speed of a machine gun. The results proved convincing as, by 1990, no more smallpox epidemics were reported by the Center for Disease Control [1,2]. Jet injection became more popular afterwards among veterinarians. Despite more th...
متن کاملDynamic control of needle-free jet injection.
Many modern pharmaceutical therapies such as vaccines and macromolecular drugs benefit from transdermal delivery. Conventional transdermal drug delivery via hypodermic needles causes pain, non-compliance, and potential contamination. Alternative transdermal strategies that deliver drugs in a quick, reliable, painless, and inexpensive way are needed. Jet injectors, which deliver drugs through th...
متن کاملInjection Characteristics of Liquid Jet from a Needle Free Injection Device in the Tissue Simulant
This study aims to investigate the dynamics characteristics of liquid jet injected from a needle-free injection device by analyzing the the flow visualization from the high-speed video camera and the CFD calculation. This is to investigate the jet flow phenomena (e.g. penetration, dispersion, velocity) in the quiescent air and in the tissue simulant (20% polyacrylamide gel) as the further infor...
متن کاملAn Evolutionary Approachs in Development of Needle Free Injection Technologies
The demand for novel drug delivery technologies is ever increasing though majority of the drugs are administered via oral, inhalation, transdermal and parenteral route. However, there are large numbers of therapies, particularly protein-based, gene-based and vaccine-based that cannot be delivered by this route for example insulin, growth hormones and other similar biologics. This emerging techn...
متن کاملImproved Pharmacokinetic and Pharmacodynamic Profile of Rapid-Acting Insulin Using Needle-Free Jet Injection Technology
OBJECTIVE Insulin administered by jet injectors is dispensed over a larger subcutaneous area than insulin injected with a syringe, which may facilitate a more rapid absorption. This study compared the pharmacologic profile of administration of insulin aspart by jet injection to that by conventional insulin pen. RESEARCH DESIGN AND METHODS Euglycemic glucose clamp tests were performed in 18 he...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Clinical, Cosmetic and Investigational Dermatology
سال: 2018
ISSN: 1178-7015
DOI: 10.2147/ccid.s162724